Kefir fermented milk and kefiran promot... [Int J Food Microbiol. 2014] - PubMed - NCBI:
The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced in one or a population of cells. It differs ..
Int J Food Microbiol. 2014 May 16;178:50-9. doi: 10.1016/j.ijfoodmicro.2014.02.024. Epub 2014 Mar 11.
Kefir fermented milk and kefiran promote growth of Bifidobacterium bifidum PRL2010 and modulate its gene expression.
Serafini F1, Turroni F2, Ruas-Madiedo P3, Lugli GA1, Milani C1, Duranti S1, Zamboni N1, Bottacini F2, van Sinderen D2, Margolles A3, Ventura M4.
Abstract
Altogether, these data support the use of kefir as a valuable means for the delivery of effective microbial cells in probiotic therapy.
Bifidobacteria constitute one of the dominant groups of microorganisms colonizing the human gut of infants. Their ability to utilize various host-derived glycans as well as dietary carbohydrates has received considerable scientific attention. However, very little is known about the role of fermented foods, such as kefir, or their constituent glycans, such as kefiran, as substrates for bifidobacterial growth and for the modulation of the expression of bifidobacterial host-effector molecules.
- Here, we show that Bifidobacterium bifidum PRL2010 exhibits high growth performance among the bifidobacterial strains tested when cultivated on kefir and/or kefiran polymer.
- Furthermore, a 16S rRNA metagenomic approach revealed that the microbiota of kefir is modified upon the addition of PRL2010 cells to the kefir matrix.
- Finally, our results show that kefir and kefiran are able to influence the transcriptome of B. bifidum PRL2010 causing increased transcription of genes involved in the metabolism of dietary glycans as well as genes that act as host-microbe effector molecules such as pili.
Bifidobacterium bifidum (strain PRL2010) - UniProt
www.uniprot.org/taxonomy/702459
Mnemonic, BIFBP. Taxon identifier, 702459. Scientific name, Bifidobacterium bifidum (strain PRL2010). Common name, -. Synonym, -. Other names ...
16S ribosomal RNA - Wikipedia, the free encyclopedia
en.wikipedia.org/wiki/16S_ribosomal_RNA
16S ribosomal RNA (or 16S rRNA) is a component of the 30S small subunit of prokaryotic ribosomes. The genes coding for it are referred to as 16S rDNA and ...
Metagenomics - Wikipedia, the free encyclopedia
en.wikipedia.org/wiki/Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental...
Transcriptome - Wikipedia, the free encyclopedia
en.wikipedia.org/wiki/Transcriptome
