The tight junctions form a seal between absorption cells, preventing any species from leaking directly from the gut to the extracellular fluid, or vice versa. This helps maintain the concentration gradients the the enterocytes use to drive nutrient absorption. In addition, the tight junctions serve as a barrier between the apical and baso-lateral membranes. If the passive and active transporters were free to move between them, there would be no net flow of nutrients into or out of the gut.
Monday, 21 July 2014
Tight Junctions | sjrz8b
Tight Junctions | sjrz8b

The tight junctions form a seal between absorption cells, preventing any species from leaking directly from the gut to the extracellular fluid, or vice versa. This helps maintain the concentration gradients the the enterocytes use to drive nutrient absorption. In addition, the tight junctions serve as a barrier between the apical and baso-lateral membranes. If the passive and active transporters were free to move between them, there would be no net flow of nutrients into or out of the gut.
The tight junctions form a seal between absorption cells, preventing any species from leaking directly from the gut to the extracellular fluid, or vice versa. This helps maintain the concentration gradients the the enterocytes use to drive nutrient absorption. In addition, the tight junctions serve as a barrier between the apical and baso-lateral membranes. If the passive and active transporters were free to move between them, there would be no net flow of nutrients into or out of the gut.
Gelatin has glutamic acid of 10%,- Amino acid composition, Wikipedia
Gelatin - Wikipedia, the free encyclopedia
Amino acid composition
Although gelatin is 98-99% protein by dry weight, it has less nutritional value than many other complete protein sources. Gelatin is unusually high in the non-essential amino acids glycine and proline (i.e., those produced by the human body), while lacking certain essential amino acids (i.e., those not produced by the human body). It contains no tryptophan and is deficient in isoleucine, threonine, and methionine.
The approximate amino acid composition of gelatin is:
Gelatin is also a topical haemostatic. A piece of gelatin sponge of appropriate size is applied on bleeding wound, pressed for some time and tied in bandage. Haemostatic action is based on platelets damage at the contact of blood with gelatin, which activates the coagulation cascade. Gelatin also causes a tamponading effect - blood flow stoppage into a blood vessel by a constriction of the vessel by an outside force.[14][page needed]
It has been claimed that oral gelatin consumption has a beneficial therapeutic effect on hair loss in both men and women.[15][16][17][18][19][20][21][22]In addition there are scientific publications that present evidence that consumption of oral gelatin has beneficial effect for some fingernail changes and diseases.[23][24][25][26]
Amino acid composition
Although gelatin is 98-99% protein by dry weight, it has less nutritional value than many other complete protein sources. Gelatin is unusually high in the non-essential amino acids glycine and proline (i.e., those produced by the human body), while lacking certain essential amino acids (i.e., those not produced by the human body). It contains no tryptophan and is deficient in isoleucine, threonine, and methionine.
The approximate amino acid composition of gelatin is:
- glycine 21%,
- proline 12%,
- hydroxyproline 12%,
- glutamic acid 10%,
- alanine 9%,
- arginine 8%,
- aspartic acid 6%,
- lysine 4%,
- serine 4%,
- leucine 3%,
- valine 2%,
- phenylalanine 2%,
threonine 2%, i - soleucine 1%,
hydroxylysine 1%,
methionine and histidine
<1% and tyrosine <0.5%.
Gelatin is also a topical haemostatic. A piece of gelatin sponge of appropriate size is applied on bleeding wound, pressed for some time and tied in bandage. Haemostatic action is based on platelets damage at the contact of blood with gelatin, which activates the coagulation cascade. Gelatin also causes a tamponading effect - blood flow stoppage into a blood vessel by a constriction of the vessel by an outside force.[14][page needed]
It has been claimed that oral gelatin consumption has a beneficial therapeutic effect on hair loss in both men and women.[15][16][17][18][19][20][21][22]In addition there are scientific publications that present evidence that consumption of oral gelatin has beneficial effect for some fingernail changes and diseases.[23][24][25][26]
Moderate alcohol consumption and small intestinal bacterial overgrowth, study finds -- ScienceDaily
Moderate alcohol consumption is associated with small intestinal bacterial overgrowth, study finds -- ScienceDaily
Just one drink per day for women -- two for men -- could lead to small intestinal bacterial overgrowth (SIBO) and subsequently cause gastrointestinal symptoms like bloating, gas, abdominal pain, constipation and diarrhea, according to the results of a new study unveiled at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC.
The retrospective review, "Moderate Alcohol Consumption is Associated with Small Intestinal Bacterial Overgrowth," looked at the charts of 198 patients who underwent lactulose hydrogen breath testing (LHBT) to determine the presence of SIBO, and found that any current alcohol consumption was significantly associated with the presence of SIBO -- and neither smoking nor use of heartburn drugs called PPIs was associated with an increased risk of SIBO.
Small intestinal bacterial overgrowth is a condition where abnormally large numbers of bacteria grow in the small intestine. Normally the small intestine contains a relatively low number of bacteria in contrast to the large intestine, which should contain a larger number of bacteria. In patients with SIBO, the abnormally large numbers of bacteria in the small intestine use for their growth many of the nutrients that would otherwise be absorbed.
As a result, a person with small bowel bacterial overgrowth may not absorb enough nutrients and become malnourished. In addition, the breakdown of nutrients by the bacteria in the small intestines can produce gas as well as lead to a change in bowel habits.
While previous studies have focused on alcoholics, who were found to have high rates of SIBO, this study by Scott Gabbard, MD and colleagues at the Dartmouth-Hitchcock Medical Center and the Mayo Clinic, is one of the first to look at the relationship between moderate alcohol consumption and SIBO. Moderate alcohol consumption means no more than 1 drink per day for women and 2 drinks per day for men, with twelve ounces of regular beer, 5 ounces of wine, or 1-1⁄2 ounces of 80-proof distilled spirits counting as one drink, according to the USDA dietary guidelines.
An overwhelming majority (95 percent) of the 198 patients in the study drank a moderate amount of alcohol, sometimes less than 1 drink per day, said Dr. Gabbard, who also indicated that only four of the patients drank more alcohol -- a finding he noted indicates that consumption of even the slightest amount of alcohol could have an impact on gut health.
"These findings are significant because we now know that any bit of alcohol consumption--not just the amount consumed by alcoholics -- is a strong predictor of a positive lactulose hydrogen breath testing and small intestinal bacterial overgrowth," he said. "While typical treatment for SIBO has been antibiotics, probiotics or a combination of the two, the question now becomes what is the exact association between moderate alcohol consumption and SIBO and whether alcohol cessation can be used as a treatment for this potentially harmful condition."
Just one drink per day for women -- two for men -- could lead to small intestinal bacterial overgrowth (SIBO) and subsequently cause gastrointestinal symptoms like bloating, gas, abdominal pain, constipation and diarrhea, according to the results of a new study unveiled at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC.
The retrospective review, "Moderate Alcohol Consumption is Associated with Small Intestinal Bacterial Overgrowth," looked at the charts of 198 patients who underwent lactulose hydrogen breath testing (LHBT) to determine the presence of SIBO, and found that any current alcohol consumption was significantly associated with the presence of SIBO -- and neither smoking nor use of heartburn drugs called PPIs was associated with an increased risk of SIBO.
Small intestinal bacterial overgrowth is a condition where abnormally large numbers of bacteria grow in the small intestine. Normally the small intestine contains a relatively low number of bacteria in contrast to the large intestine, which should contain a larger number of bacteria. In patients with SIBO, the abnormally large numbers of bacteria in the small intestine use for their growth many of the nutrients that would otherwise be absorbed.
As a result, a person with small bowel bacterial overgrowth may not absorb enough nutrients and become malnourished. In addition, the breakdown of nutrients by the bacteria in the small intestines can produce gas as well as lead to a change in bowel habits.
While previous studies have focused on alcoholics, who were found to have high rates of SIBO, this study by Scott Gabbard, MD and colleagues at the Dartmouth-Hitchcock Medical Center and the Mayo Clinic, is one of the first to look at the relationship between moderate alcohol consumption and SIBO. Moderate alcohol consumption means no more than 1 drink per day for women and 2 drinks per day for men, with twelve ounces of regular beer, 5 ounces of wine, or 1-1⁄2 ounces of 80-proof distilled spirits counting as one drink, according to the USDA dietary guidelines.
An overwhelming majority (95 percent) of the 198 patients in the study drank a moderate amount of alcohol, sometimes less than 1 drink per day, said Dr. Gabbard, who also indicated that only four of the patients drank more alcohol -- a finding he noted indicates that consumption of even the slightest amount of alcohol could have an impact on gut health.
"These findings are significant because we now know that any bit of alcohol consumption--not just the amount consumed by alcoholics -- is a strong predictor of a positive lactulose hydrogen breath testing and small intestinal bacterial overgrowth," he said. "While typical treatment for SIBO has been antibiotics, probiotics or a combination of the two, the question now becomes what is the exact association between moderate alcohol consumption and SIBO and whether alcohol cessation can be used as a treatment for this potentially harmful condition."
Damage to Gut Flora is Not Repaired by Diet Alone - Cooling Inflammation: Dr. Oz on Gut Flora Repair
Cooling Inflammation: Dr. Oz on Gut Flora Repair
Damage to Gut Flora is Not Repaired by Diet Alone
There is little or no effort being made by the medical industry to develop approaches to repair gut flora damaged by disease, unhealthy diets or medical procedures. This is similar to a surgeon stepping away from removal of a diseased organ without closing the wound. Antibiotics leave a gut flora that will remain permanently damaged without systematic, monitored repair. It might also be suspected that disruption of gut flora by antibiotics and the introduction of large amounts of new foods, such as high fructose corn syrup and vegetable oils may contribute to or cause the modern prominence of obesity. After all, gain or loss of weight changes gut flora, obese individuals have damaged gut flora, and trading gut flora between fat and lean animals, trades weight gain/loss behaviors.
Sources of Bacteria to Repair Damaged Gut Flora
We must eat new bacteria in order to replace bacterial species lost by antibiotics or unhealthy diets:
- Probiotics ----------- specialized bacteria that grow in milk products
- Spices and herbs --- plant products abundantly contaminated with bacteria that digest plants
- Fresh vegetables --- bacteria are on the surfaces of plants unless the vegetables are cleaned or
cooked
- Fermented foods --- bacterial growth leading to acid or alcohol production has beed used in the
preparation and storage of many foods and provides a rich bacterial resources
Environment -- Bacteria are transferred to our hands and face from other people, pets and surfaces,
unless hands and the body are continually washed. Sanitizers and frequent washing
of hands and surfaces eliminate acquisition of environmental bacteria to repair
damaged gut flora. Social isolation and hygiene block repair of gut flora
Replacement -- experimental replacement of damaged with healthy gut flora (fecal transplant) has been very effective in curing many diseases without significant risks, but is restricted by the medical industry.
Damage to Gut Flora is Not Repaired by Diet Alone
There is little or no effort being made by the medical industry to develop approaches to repair gut flora damaged by disease, unhealthy diets or medical procedures. This is similar to a surgeon stepping away from removal of a diseased organ without closing the wound. Antibiotics leave a gut flora that will remain permanently damaged without systematic, monitored repair. It might also be suspected that disruption of gut flora by antibiotics and the introduction of large amounts of new foods, such as high fructose corn syrup and vegetable oils may contribute to or cause the modern prominence of obesity. After all, gain or loss of weight changes gut flora, obese individuals have damaged gut flora, and trading gut flora between fat and lean animals, trades weight gain/loss behaviors.
Sources of Bacteria to Repair Damaged Gut Flora
We must eat new bacteria in order to replace bacterial species lost by antibiotics or unhealthy diets:
- Probiotics ----------- specialized bacteria that grow in milk products
- Spices and herbs --- plant products abundantly contaminated with bacteria that digest plants
- Fresh vegetables --- bacteria are on the surfaces of plants unless the vegetables are cleaned or
cooked
- Fermented foods --- bacterial growth leading to acid or alcohol production has beed used in the
preparation and storage of many foods and provides a rich bacterial resources
Environment -- Bacteria are transferred to our hands and face from other people, pets and surfaces,
unless hands and the body are continually washed. Sanitizers and frequent washing
of hands and surfaces eliminate acquisition of environmental bacteria to repair
damaged gut flora. Social isolation and hygiene block repair of gut flora
Replacement -- experimental replacement of damaged with healthy gut flora (fecal transplant) has been very effective in curing many diseases without significant risks, but is restricted by the medical industry.
About Me

- Dr. Art Ayers
- I grew up in San Diego and did my PhD in Molecular, Cellular and Developmental Biology (U. Colo. Boulder). I subsequently held postdoctoral research positions at the Swedish Forest Products Research Laboratories, Stockholm, U. Missouri -Colombia and Kansas State U. I was an assistant professor in the Cell and Developmental Biology Department at Harvard University, and an associate professor and Director of the Genetic Engineering Program at Cedar Crest College in Allentown, PA. I joined the faculty at the College of Idaho in 1991 and in 1997-98 I spent a six-month sabbatical at the National University of Singapore. Most recently I have focused on the role of heparin in inflammation and disease.
The amount of resistant starch is related to the amount of protein in the tuber or grain/seed Feeding the Microbiota: Non-Starch Polysaccharides (NSP), Resistant Starch (RS) and Mucous
Animal Pharm: Feeding the Microbiota: Non-Starch Polysaccharides (NSP), Resistant Starch (RS) and Mucous
Evolution of RS
The amount of resistant starch appears to me to be related to the amount of protein in the tuber or grain/seed, on cursory review. I've tried to dig further but can't find anything. The food sources which appear to have the most RS are the starch containing foods with intact cell walls and higher protein content legumes (9.5-11.1% dal, lentils, beans), whole grains (4.5-6%), or complete proteins (2% potato; 4.8-5.9% processed non-modified PS; steamed/cooled potato 31% and roasted/cooled potato 52.5%). Perhaps amylose and other RS protect the peptides embedded in the starch matrix for tuber and grain/seed winter storage to buffer the Ice Age chill? Sprouting and germinating grains/seeds raise protein and nutritional content, but lowers RS. Additionally, fermentation of starches is a trade-off -- fermentation lowers RS but raises protein/vitamin content.
Evolution of RS
The amount of resistant starch appears to me to be related to the amount of protein in the tuber or grain/seed, on cursory review. I've tried to dig further but can't find anything. The food sources which appear to have the most RS are the starch containing foods with intact cell walls and higher protein content legumes (9.5-11.1% dal, lentils, beans), whole grains (4.5-6%), or complete proteins (2% potato; 4.8-5.9% processed non-modified PS; steamed/cooled potato 31% and roasted/cooled potato 52.5%). Perhaps amylose and other RS protect the peptides embedded in the starch matrix for tuber and grain/seed winter storage to buffer the Ice Age chill? Sprouting and germinating grains/seeds raise protein and nutritional content, but lowers RS. Additionally, fermentation of starches is a trade-off -- fermentation lowers RS but raises protein/vitamin content.
Appendix a safe house for good bacteria, used to effectively reboot the gut - ABC News (Australian Broadcasting Corporation)
Scientists discover true function of appendix organ - ABC News (Australian Broadcasting Corporation)
Scientists say the appendix might have been a place for good
bacteria to localise in, like a little cul-de-sac away from everything
else [File photo].
It has long been regarded as a potentially troublesome, redundant organ, but American researchers say they have discovered the true function of the appendix.
The researchers say it acts as a safe house for good bacteria, which can be used to effectively reboot the gut following a bout of dysentery or cholera.
The conventional wisdom is that the small pouch protruding from the first part of the large intestine is redundant and many people have their appendix removed and appear none the worse for it.
Scientists from the Duke University Medical Centre in North Carolina say following a severe bout of cholera or dysentery, which can purge the gut of bacteria essential for digestion, the reserve good bacteria emerge from the appendix to take up the role.
But Professor Bill Parker says the finding does not mean we should cling onto our appendices at all costs.
"It's very important for people to understand that if their appendix gets inflamed, just because it has a function it does not mean they should try to keep it in," he said.
"So it's sort of a fun thing that we've found, but we don't want it to cause any harm, we don't want people to say, "oh, my appendix has a function", so I'm not going to go to the doctor, I'm going to try to hang onto it."
Attractive theory
Nicholas Vardaxis, an associate professor in the Department of Medical Sciences at RMIT University, says the theory put forward by the Duke University scientists makes sense.
"As an idea it's an attractive one, that perhaps it would be a nice place for these little bacteria to localise in, a little cul-de-sac away from everything else," he said.
"The thing is that if we observe what's been happening through evolution, the higher on the evolutionary scale we are and the more omnivorous animals become, then the smaller and less important the appendix becomes and humans are a good example of that.
"The actual normal flora bacteria within the appendix, as well within our gut, are the same, so we've lost all of those specialised bacteria.
"So it doesn't have that safe house type of function anymore, I don't think.
"It's a vestige of something that was there in previous incarnations, if you like."
Koala appendix
Unlike the human, the koala is famous for having a very long appendix.
It is thought to aid digestion on a diet made up exclusively of eucalyptus leaves.
Professor Vardaxis says that is not likely to change any time soon.
"Unless of course we have a massive blight and we get the eucalypt on which the koala thrives dying, then we may find some mutant koalas out there perhaps that will start eating other things, and as they start to eat other things, then over generations and hundreds of thousands of years of time, then surely, yes, the koala's appendix will shrink as well," he said.
Professor Vardaxis says it is possible that at that point, koalas might be afflicted by appendicitis and have to have it taken out at times.
Wed 10 Oct 2007, 8:35am AEST
Scientists say the appendix might have been a place for good
bacteria to localise in, like a little cul-de-sac away from everything
else [File photo].
The researchers say it acts as a safe house for good bacteria, which can be used to effectively reboot the gut following a bout of dysentery or cholera.
The conventional wisdom is that the small pouch protruding from the first part of the large intestine is redundant and many people have their appendix removed and appear none the worse for it.
Scientists from the Duke University Medical Centre in North Carolina say following a severe bout of cholera or dysentery, which can purge the gut of bacteria essential for digestion, the reserve good bacteria emerge from the appendix to take up the role.
But Professor Bill Parker says the finding does not mean we should cling onto our appendices at all costs.
"It's very important for people to understand that if their appendix gets inflamed, just because it has a function it does not mean they should try to keep it in," he said.
"So it's sort of a fun thing that we've found, but we don't want it to cause any harm, we don't want people to say, "oh, my appendix has a function", so I'm not going to go to the doctor, I'm going to try to hang onto it."
Attractive theory
Nicholas Vardaxis, an associate professor in the Department of Medical Sciences at RMIT University, says the theory put forward by the Duke University scientists makes sense.
"As an idea it's an attractive one, that perhaps it would be a nice place for these little bacteria to localise in, a little cul-de-sac away from everything else," he said.
"The thing is that if we observe what's been happening through evolution, the higher on the evolutionary scale we are and the more omnivorous animals become, then the smaller and less important the appendix becomes and humans are a good example of that.
"The actual normal flora bacteria within the appendix, as well within our gut, are the same, so we've lost all of those specialised bacteria.
"So it doesn't have that safe house type of function anymore, I don't think.
"It's a vestige of something that was there in previous incarnations, if you like."
Koala appendix
Unlike the human, the koala is famous for having a very long appendix.
It is thought to aid digestion on a diet made up exclusively of eucalyptus leaves.
Professor Vardaxis says that is not likely to change any time soon.
"Unless of course we have a massive blight and we get the eucalypt on which the koala thrives dying, then we may find some mutant koalas out there perhaps that will start eating other things, and as they start to eat other things, then over generations and hundreds of thousands of years of time, then surely, yes, the koala's appendix will shrink as well," he said.
Professor Vardaxis says it is possible that at that point, koalas might be afflicted by appendicitis and have to have it taken out at times.
How diet absolutely shifts bacterial communities in the gut ecology: Feeding the Microbiota: Non-Starch Polysaccharides (NSP), Resistant Starch (RS) and Mucous
Animal Pharm: Feeding the Microbiota: Non-Starch Polysaccharides (NSP), Resistant Starch (RS) and Mucous
For SIBO and intestinal permeability, it's actually healing to minimize fermentation if it is occurring pathogically in the small intestines... where it shouldn't be. The surface of the small intestines is not designed to support extensive networks of microbial growth which requires thick mucous. The integrity of the small intestines can easilybe compromised and fail to serve its function (digestion and absorption) when inappropriate growth manages to perpetuate whether it's'good' v 'pathogenic' bacteria, yeasts or mycobacteria or parasites/worms.
Diet absolutely shifts bacterial communities in the gut ecology -- simple sugars lowers the good, raises the bad. More fiber and RS both raise the good (in Bacteroidetes -- Prevotella, etc), lowers the bad (in Firmicutes -- virulent strains of clostridas, E. coli's, enterococci, streps). This is borne out in pig, children and human studies. Flint et al do a great review here which includes a raffinose study (fiber from legumes) that enriched and ↑ F. prausnitzii, Bifidobacterium spp.
Like many of the good gut flora, Bifidobacter tightens up the intestinal tight junctions as super tight as a nun's **ss,
which is enteroproctive and immunoprotective again gastroenteritis, intestinal permeability and necrotizing enterocolitis in trials. Guess
what? Magnesium deficiency compromises Bifidobacter and intestinal permeability (or which came first?). Bifido appears to enjoy magnesium. Inrodent studies fed a mag-deficient diet, intestinal permeability and quantitative changes to cecal bifidobacteria were associated.
Below is a human study n=10 on the microbiota shifts comparing RS2 and
RS4 intakes (55 grams/day x3wks, then 2 wk washout). Even among
resistant starches, there is selective species enrichment.
The authors state in the results: "Ten human subjects consumed crackers
for three weeks each containing either RS2, RS4, or native starch in a
double-blind, crossover design. Multiplex sequencing of 16S rRNA tags
revealed that both types of RS induced several significant compositional
alterations in the fecal microbial populations, with differential
effects on community structure.
RS4 but not RS2 induced phylum-levelchanges, significantly increasing Actinobacteria and Bacteroidetes (+++) while decreasing Firmicutes(-). At the species level, the changes evoked by RS4 were increases in Bifidobacterium adolescentis and Parabacteroides distasonis, while RS2 significantly raised the proportions of Ruminococcus bromii and Eubacterium rectale
when compared to RS4. The population shifts caused by RS4 were numerically substantial for several taxa, leading for example, to a ten-fold increase in bifidobacteria in three of thesubjects, enriching them to 18–30% of the fecal microbial community. Theresponses to RS and their magnitudes variedbetween individuals, and they were reversible and tightly associated with the consumption of RS."
Shifting Microbiota Communities: GI Fx Stool Test and Optimal Nutri Eval (ONE)
Would you like to do a GI fx stool test and see your microbiota and do a
ONE to evaluate nutrient deficiencies, dysbiotic markers and 8OHdG (DNA
damage)? Let me know and show me! (Cost $99 and $129, respectively,
plus admin fee $50). Let's conduct paleo gut experiments.
Brent Pottenger's case: Recall his Prevotella, Bacteroidetes and Firmicutes are quite stunning
and no biomarkers of dysbiosis. He has likely very little mercury (no
history of cavities). His diet: near carnivory, fermented full fat Greek
+ some veggies both raw/cook (per Pottenger's cats). The microbiota
sequencing reveals a beautiful display of healthy guts. Previously he
c/o acne and migraines which are signs of SIBO and intestinal
permeability.
My case: The Prevotella, Bacteroidetes and Firmicutes (2013)
are impressively improved and robust compared with the initial 2011
when I had CFS, fogginess, fraility (sarcopenia), rank mood, and on/off
body fat. The SIBO is gone except for residual dysbiotic biomarkers
from a parasite and Morganella.
What had I done?
--for two years
For SIBO and intestinal permeability, it's actually healing to minimize fermentation if it is occurring pathogically in the small intestines... where it shouldn't be. The surface of the small intestines is not designed to support extensive networks of microbial growth which requires thick mucous. The integrity of the small intestines can easilybe compromised and fail to serve its function (digestion and absorption) when inappropriate growth manages to perpetuate whether it's'good' v 'pathogenic' bacteria, yeasts or mycobacteria or parasites/worms.
Diet absolutely shifts bacterial communities in the gut ecology -- simple sugars lowers the good, raises the bad. More fiber and RS both raise the good (in Bacteroidetes -- Prevotella, etc), lowers the bad (in Firmicutes -- virulent strains of clostridas, E. coli's, enterococci, streps). This is borne out in pig, children and human studies. Flint et al do a great review here which includes a raffinose study (fiber from legumes) that enriched and ↑ F. prausnitzii, Bifidobacterium spp.
Like many of the good gut flora, Bifidobacter tightens up the intestinal tight junctions as super tight as a nun's **ss,
which is enteroproctive and immunoprotective again gastroenteritis, intestinal permeability and necrotizing enterocolitis in trials. Guess
what? Magnesium deficiency compromises Bifidobacter and intestinal permeability (or which came first?). Bifido appears to enjoy magnesium. Inrodent studies fed a mag-deficient diet, intestinal permeability and quantitative changes to cecal bifidobacteria were associated.
Below is a human study n=10 on the microbiota shifts comparing RS2 and
RS4 intakes (55 grams/day x3wks, then 2 wk washout). Even among
resistant starches, there is selective species enrichment.
The authors state in the results: "Ten human subjects consumed crackers
for three weeks each containing either RS2, RS4, or native starch in a
double-blind, crossover design. Multiplex sequencing of 16S rRNA tags
revealed that both types of RS induced several significant compositional
alterations in the fecal microbial populations, with differential
effects on community structure.
RS4 but not RS2 induced phylum-levelchanges, significantly increasing Actinobacteria and Bacteroidetes (+++) while decreasing Firmicutes(-). At the species level, the changes evoked by RS4 were increases in Bifidobacterium adolescentis and Parabacteroides distasonis, while RS2 significantly raised the proportions of Ruminococcus bromii and Eubacterium rectale
when compared to RS4. The population shifts caused by RS4 were numerically substantial for several taxa, leading for example, to a ten-fold increase in bifidobacteria in three of thesubjects, enriching them to 18–30% of the fecal microbial community. Theresponses to RS and their magnitudes variedbetween individuals, and they were reversible and tightly associated with the consumption of RS."
Shifting Microbiota Communities: GI Fx Stool Test and Optimal Nutri Eval (ONE)
Would you like to do a GI fx stool test and see your microbiota and do a
ONE to evaluate nutrient deficiencies, dysbiotic markers and 8OHdG (DNA
damage)? Let me know and show me! (Cost $99 and $129, respectively,
plus admin fee $50). Let's conduct paleo gut experiments.
Brent Pottenger's case: Recall his Prevotella, Bacteroidetes and Firmicutes are quite stunning
and no biomarkers of dysbiosis. He has likely very little mercury (no
history of cavities). His diet: near carnivory, fermented full fat Greek
+ some veggies both raw/cook (per Pottenger's cats). The microbiota
sequencing reveals a beautiful display of healthy guts. Previously he
c/o acne and migraines which are signs of SIBO and intestinal
permeability.
My case: The Prevotella, Bacteroidetes and Firmicutes (2013)
are impressively improved and robust compared with the initial 2011
when I had CFS, fogginess, fraility (sarcopenia), rank mood, and on/off
body fat. The SIBO is gone except for residual dysbiotic biomarkers
from a parasite and Morganella.
What had I done?
--for two years
- gluten free, casein free, exercise/yoga (some barefoot on soil/lawn)
- removed mercury, gold, titanium parts and oral chelation on/off
- sleep, adrenal/gut support, antioxidants incl pycnogenol, omega-3, minerals
- Prescript Assist, FloraMend
- whole food diet (rainbow tubers, veggies, organic meat, lard/ghee)
- fermented pao cai, Beijing radishes, carrots
- Seed: Raw unpasteruized sauerkraut at nearly every meal and drank the brine, SBO probiotics
- Weed: charcoal and bentonite clay; removed gut irritants (alcohol -- studies here and here)
- Feed: Kraut and fiber rich foods (basmati rice, vegetables, potatoes, etc)
Beta-glucan is a special soluble fiber (NSP) - Feeding the Microbiota: Non-Starch Polysaccharides (NSP), Resistant Starch (RS) and Mucous
Animal Pharm: Feeding the Microbiota: Non-Starch Polysaccharides (NSP), Resistant Starch (RS) and Mucous
Beta-glucan is a special soluble fiber (NSP)-- it's not made by mammals.
It's found in yeast cell walls, whole grains, and mushrooms. It's been
shown to not only affect the microbiota but also improve immune
function, wound healing, metabolic dysregulation, cancer/tumour sizes,
and inflammation.
A recent study tracked the fate of beta-glucan in the
gut and immune lymphoid tissues. Researchers
found "these large -1,3-glucans were taken up by gastrointestinal
macrophages and shuttled to reticuloendothelial tissues and bone marrow.
Within the marrow, the macrophages degraded the -1,3-glucan and
secreted small soluble biologically active fragments that bound to CR3
of mature bone marrow granulocytes. Once recruited from the bone marrow
by an inflammatory stimulus, these granulocytes with -1,3-glucan-primed
CR3 could kill iC3b-coated tumor cells."
Resistant starch (RS) is found to be quite as plentiful as beta-glucan
and plant fibers however cooking breaks it down to a form that we can
digest (enzymatic, mastication, acidic). The amount remaining in a food
that escapes our digestive juices varies by many factors -- species,
maturity of the plant, cooking/cooling methods, food acidity, to name
just a few. RS is different from beta-glucan and fiber due to its
tightly bound double helical glucose polymer structure. Yes it is coiled up like DNA....
Solubilization in cooking water 'releases' the starches into a gelatin
matrix which our spit amylases and pancreatic carb-ases can breakdown
to glucose for absorption in the stomach and small intestine. Any
undigested amounts enter the caecum and colon. The amount of SFCA
produced upon caecal and colon fermentation varies as well depending on
an individuals microbiota species, large intestine health status, etc.
Beta-glucan is a special soluble fiber (NSP)-- it's not made by mammals.
It's found in yeast cell walls, whole grains, and mushrooms. It's been
shown to not only affect the microbiota but also improve immune
function, wound healing, metabolic dysregulation, cancer/tumour sizes,
and inflammation.
A recent study tracked the fate of beta-glucan in the
gut and immune lymphoid tissues. Researchers
found "these large -1,3-glucans were taken up by gastrointestinal
macrophages and shuttled to reticuloendothelial tissues and bone marrow.
Within the marrow, the macrophages degraded the -1,3-glucan and
secreted small soluble biologically active fragments that bound to CR3
of mature bone marrow granulocytes. Once recruited from the bone marrow
by an inflammatory stimulus, these granulocytes with -1,3-glucan-primed
CR3 could kill iC3b-coated tumor cells."
Resistant starch (RS) is found to be quite as plentiful as beta-glucan
and plant fibers however cooking breaks it down to a form that we can
digest (enzymatic, mastication, acidic). The amount remaining in a food
that escapes our digestive juices varies by many factors -- species,
maturity of the plant, cooking/cooling methods, food acidity, to name
just a few. RS is different from beta-glucan and fiber due to its
tightly bound double helical glucose polymer structure. Yes it is coiled up like DNA....
Solubilization in cooking water 'releases' the starches into a gelatin
matrix which our spit amylases and pancreatic carb-ases can breakdown
to glucose for absorption in the stomach and small intestine. Any
undigested amounts enter the caecum and colon. The amount of SFCA
produced upon caecal and colon fermentation varies as well depending on
an individuals microbiota species, large intestine health status, etc.
Prescript-Assist® – Soil Based Probiotic | Health Scene Australia
Prescript-Assist® – Soil Based Probiotic | Health Scene Australia
FREE Shipping on orders over AU$69.00 in Australia
Prescript-Assist® (P-A) is a 3rd-generation combination of >29
probiotic microflora “Soil-Based-Organisms (SBOs)” uniquely combined
with a humic/fulvic acid prebiotic that enhances SBO proliferation.
Prescript-Assist’s® microflora are Class-1 micro ecological units that
are typical of those progressively found resident along the healthy
human GI Track. And, with more than 5 years in clinical development and
testing*, Prescript-Assist remains one of the most effective probiotic
supplements for restoring levels of gastrointestinal micro-flora
compromised from antibiotics, medication, poor diet, stress, and
digestive abnormalities.
Prescript-Assist can help with:
FREE Shipping on orders over AU$69.00 in Australia
probiotic microflora “Soil-Based-Organisms (SBOs)” uniquely combined
with a humic/fulvic acid prebiotic that enhances SBO proliferation.
Prescript-Assist’s® microflora are Class-1 micro ecological units that
are typical of those progressively found resident along the healthy
human GI Track. And, with more than 5 years in clinical development and
testing*, Prescript-Assist remains one of the most effective probiotic
supplements for restoring levels of gastrointestinal micro-flora
compromised from antibiotics, medication, poor diet, stress, and
digestive abnormalities.
Prescript-Assist can help with:
- Maintain Healthy GI-Track MicroFloral Ecologies
- Promote Normal Bowel Function
- Support Gut Immune-System
- Assist in Stabilizing the Gut Mucosal Barrier
- Support Normal Absorption and Assimilation of Nutrients in the Gut
Resistant starch: necessary for good health or latest fad?
Resistant starch: necessary for good health or latest fad?
Ihave been getting some RS in my diet. I may increase it a little bit,
but I think it is the increase in starch in general that is most
important for me. My eyes are tearing up again!
White beans (small navy variety) have always been GAPS friendly, and I have consumed
them, along with lentils, pretty much once a week for awhile now. Like
the last couple of years.
Prescript Assist is something I tried1-2 years ago and it
caused me major flatulence. We began to lovingly
refer to it as Divorce Assist, as that is the result it had on all 4
family members. Well, guess what? We are all on day 5 of a light
protocol of it without any issue. Nothing. So when this bottle runs
out, that will be the end of that for now. I figure I will be feeding
the strains and not going overboard in any direction, and whatever will
be will be. I think my gut health is in pretty fine shape due in large
part to the home prepared wild and BE cultured fermented foods I have
consumed since circa 2005 on a very regular basis.
Yeah, I know that sprouts turn starches to sugars to some extent. But, mung beans
are still starchy when sprouted, and I needed starch, so there. And I
still have a big bag left in the fridge.
I think the RS choices that would/do work for me include, by rank:
1. white beans
2. black beans
3. lentils
4. mung beans
5. corn masa (I get really good quality organic masa from Gold Mine Foods)
6. buckwheat (but I always sprout this first)
Yeah, that has always been the fear on GAPS/SCD that starches would fuel
SIBO. And so I would probably not concern myself too much with dosing
on raw potato starch or similar weirdness. If it helps others, great.
But I would probably think more in terms of proper preparation of foods
than maximizing RS. Again, a big picture approach tends to be the best
imo to gain insight to better overall health. And ancient wisdom is
usually spot on.
White beans seem to be one of my better tolerated beans and, interestingly,
they are ranked as one of the highest legume sources of RS.
FYI: Tatertot wrote that sprouts don't contain much RS.
I'm trying Prescript Assist too, after I saw Dr. BG and others recommend it as one of the best.
Here are a couple more intros on RS.
December 17th, 2013 • 212 Comments
- A Resistant Starch Primer For Newbies
http://freetheanimal.com/2013/12/resistant-primer-newbies.html
[Warning:
this blog is uncensored and politically incorrect, and at times can get
rude, especially toward women, but Tatertot Tim and Dr. BG both pitch
in here, there are nonetheless lots of female readers and commenters,
and I'd read the Devil's blog if he was sharing useful info.]
January 19, 2014 | by Kris Gunnars | 1,760 views | 7 Comments
- Resistant Starch 101 – Everything You Need to Know
http://authoritynutrition.com/resistant-starch-101
Tatertot Tim also posts about RS at the Mark's Daily Apple forum.
Ihave been getting some RS in my diet. I may increase it a little bit,
but I think it is the increase in starch in general that is most
important for me. My eyes are tearing up again!
White beans (small navy variety) have always been GAPS friendly, and I have consumed
them, along with lentils, pretty much once a week for awhile now. Like
the last couple of years.
Prescript Assist is something I tried1-2 years ago and it
caused me major flatulence. We began to lovingly
refer to it as Divorce Assist, as that is the result it had on all 4
family members. Well, guess what? We are all on day 5 of a light
protocol of it without any issue. Nothing. So when this bottle runs
out, that will be the end of that for now. I figure I will be feeding
the strains and not going overboard in any direction, and whatever will
be will be. I think my gut health is in pretty fine shape due in large
part to the home prepared wild and BE cultured fermented foods I have
consumed since circa 2005 on a very regular basis.
Yeah, I know that sprouts turn starches to sugars to some extent. But, mung beans
are still starchy when sprouted, and I needed starch, so there. And I
still have a big bag left in the fridge.
I think the RS choices that would/do work for me include, by rank:
1. white beans
2. black beans
3. lentils
4. mung beans
5. corn masa (I get really good quality organic masa from Gold Mine Foods)
6. buckwheat (but I always sprout this first)
Yeah, that has always been the fear on GAPS/SCD that starches would fuel
SIBO. And so I would probably not concern myself too much with dosing
on raw potato starch or similar weirdness. If it helps others, great.
But I would probably think more in terms of proper preparation of foods
than maximizing RS. Again, a big picture approach tends to be the best
imo to gain insight to better overall health. And ancient wisdom is
usually spot on.
Source: Butyric Acid: an Ancient Controller of Metabolism, Inflammation and Stress Resistance?
Whole Health Source: Butyric Acid: an Ancient Controller of Metabolism, Inflammation and Stress Resistance?
Sources of Butyrate
There are two main ways to get butyrate and other short-chain fatty
acids. The first is to eat fiber and let your intestinal bacteria do
the rest. Whole plant foods such as sweet potatoes, properly prepared
whole grains, beans, vegetables, fruit and nuts are good sources of
fiber. Refined foods such as white flour, white rice and sugar are very
low in fiber. Clinical trials have shown that increasing dietary fiber
increases butyrate production, and decreasing fiber decreases it.
Sources of Butyrate
There are two main ways to get butyrate and other short-chain fatty
acids. The first is to eat fiber and let your intestinal bacteria do
the rest. Whole plant foods such as sweet potatoes, properly prepared
whole grains, beans, vegetables, fruit and nuts are good sources of
fiber. Refined foods such as white flour, white rice and sugar are very
low in fiber. Clinical trials have shown that increasing dietary fiber
increases butyrate production, and decreasing fiber decreases it.
Resisting Resistant Starch - Primal Docs
Resisting Resistant Starch - Primal Docs
EXTRACT
“Resistant starch” has become fashionable! Two blog
posts from the popular Mark’s Daily Apple
were recently devoted to it, and bloggers Richard Nikoley,
“Tatertot”Tim, and Dr. BG are reportedly writing a book
about it. It seems resistant starch is on everyone’s lips!
But I have to say I just don’t get it. Not at all!
By “resistant starch” is meant plant starch that “resists” digestion,
starch that is not turned into glucose but that instead travels
colonward unscathed, where it is supposed to feed beneficial gut
bacteria (assuming beneficial gut bacteria are there to be fed) and
create butyrate, a major fuel of local cells.
Speaking on behalf of our gut bacteria, I can certainly say that
nourishment is desirable. Of course the fibrous content of ordinary
vegetables is perfectly capable of accomplishing this, and we take
advantage of this happy scenario every time we eat some broccoli or a
cabbage or have some salad. (Eating pasture-raised meats nose to tail
doesn’t hurt, either.) Even resistant starch’s reported benefit of
increasing insulin receptor sensitivity and its corollary good things
can be simply achieved in other ways, for example, by eating a diet high
in fat, moderate in protein, and low in carbohydrate mostly from
non-starchy fibrous vegetables.
But resistant-starch aficionados point out that some foods pack an
extra punch. These foods are the energy drinks of resistant starch, as
it were.
EXTRACT
“Resistant starch” has become fashionable! Two blog
posts from the popular Mark’s Daily Apple
were recently devoted to it, and bloggers Richard Nikoley,
“Tatertot”Tim, and Dr. BG are reportedly writing a book
about it. It seems resistant starch is on everyone’s lips!
But I have to say I just don’t get it. Not at all!
By “resistant starch” is meant plant starch that “resists” digestion,
starch that is not turned into glucose but that instead travels
colonward unscathed, where it is supposed to feed beneficial gut
bacteria (assuming beneficial gut bacteria are there to be fed) and
create butyrate, a major fuel of local cells.
Speaking on behalf of our gut bacteria, I can certainly say that
nourishment is desirable. Of course the fibrous content of ordinary
vegetables is perfectly capable of accomplishing this, and we take
advantage of this happy scenario every time we eat some broccoli or a
cabbage or have some salad. (Eating pasture-raised meats nose to tail
doesn’t hurt, either.) Even resistant starch’s reported benefit of
increasing insulin receptor sensitivity and its corollary good things
can be simply achieved in other ways, for example, by eating a diet high
in fat, moderate in protein, and low in carbohydrate mostly from
non-starchy fibrous vegetables.
But resistant-starch aficionados point out that some foods pack an
extra punch. These foods are the energy drinks of resistant starch, as
it were.
Sunday, 20 July 2014
What Should You Eat To Heal a Leaky Gut? » The Paleo Mom
What Should You Eat To Heal a Leaky Gut? » The Paleo Mom
April 5, 2012 in Categories: Gut Health by ThePaleoMom
If you are concerned that you may have, or could develop, a leaky gut, then changing your diet to one that protects the gut is a natural next step for you. If you are already battling health conditions related to having a leaky gut, then you will have to be more strict with your dietary choices and also address other lifestyle factors like getting good quality sleep, managing stress, finding time for low-strain exercise, and getting outside.
The first and most important thing to do to heal a leaky gut is to stop eating foods that damage and inflame the gut lining! It can take six months or more for the gut to fully heal depending on the extent of the damage, the health of the gut microflora and your individual genetics (for people with Small Intestinal Bacterial Overgrowth, recovery can take up to two years!). Until the gut is completely healthy, it is important to abstain from all grains, all legumes, and all dairy products (some people may tolerate ghee and/or butter from grass-fed sources, but I recommend leaving it out for at least a month before trying it). It is also important to avoid additives in processed foods (many of which irritate the gut) and refined sugars (which promote inflammation). Some people will also need to eliminate vegetables from the nightshade family (tomatoes, eggplants, peppers of all kinds, and especially potatoes), eliminate egg whites (I actually rinse my egg yolks before eating them), and limit nut consumption (other than coconut and macadamias). Changing your diet to avoid gut-irritating foods is critical. But, it is also important to include foods that can reduce inflammation and help heal the damaged gut.
Eat foods that reduce inflammation. It’s very important to be mindful of both your omega-6 and your omega-3 polyunsaturatedfatty acid intake. Omega-6 polyunsaturated fats, which are found in large quantities in modern vegetable oils, meat from grain-fed animals, and many nuts and seeds, increase inflammation. Omega-3 fatty acids, which are found in large quantities in wild-caught fish, pastured/free-range eggs, and meat from pastured animals, decrease inflammation. To help reduce overall inflammation and heal the gut, aim for a 1:1 ratio of omega-3 to omega-6 fatty acid intake in your diet. There are several ways of doing this: you can make sure that all of the meat in your diet is exclusively from grass-fed animals (beef, bison, goat or lamb); you can eat plenty of wild-caught seafood; and/or you can supplement with a good quality fish oil.
Vegetables are rich in anti-oxidants, vitamins and minerals which help control inflammation (and help with just about every other normal function of the body!). Eating a variety of differently colored vegetables, a variety of dark green leafy vegetables, and a variety cruciferous vegetables (broccoli, cauliflower, cabbage, turnip greens, kale, Brussels sprouts, etc.) every day will provide all of the essential vitamins and minerals in a way that is easy for the body to absorb (no more need for a multivitamin!). Fruits, especially berries, are also a good source of antioxidants, vitamins and minerals. However, most people will need to exercise some portion control with fruits due to the high sugar content. I recommend eating vegetables at every meal (it can be a bit strange getting used to eating vegetables at breakfast, but it’s amazing what a difference it makes to how you feel for the whole rest of the day!).
It is also important to make sure you are getting enough Vitamin D. You can achieve this by simply spending some time outside in the sun every day, or from eating liver once or twice per week, or from supplementing with Cod Liver Oil or Vitamin D3 supplements.
Eat foods that restore gut microflora. If you have a leaky and inflamed gut, chances are very good that your resident good bacteria are having trouble too. To help restore their numbers and their diversity, eat as many different good sources of probiotics as possible. You can do this by taking Probiotic supplements and changing brands every time you buy a bottle (the different brands all have different proprietary strains, which helps with increasing your gut microflora diversity). Even better, you can consume probiotic rich foods, like unpasteurized Sauerkraut and other unpasteurized fermented vegetables, Kombucha Tea (my personal favorite), and coconut milk Yogurt or Kefir (which can be a little harder to find in stores but very easy to make at home). All of these can be found at alternative grocery stores (like Whole Foods), and some can be found online, but all can also be made easily and inexpensively at home.
Eat foods that promote healing: As the body tries to heal itself, it’s important to provide it with plenty of good quality protein (needed to make all those new cells and connective tissues) as well as vitamins, minerals and good fats. In this way, the best way to promote healing is to eat a paleo diet that includes wild-caught fish, meat from grass-fed sources, organ meat (preferably from pastured sources), and plenty of vegetables. There are two other healing foods that are very important to include: coconut and bone broth. Antimicrobial short- and medium-chain saturated fats, like those found in coconut oil and other coconut products, help to reduce overgrowth of bad yeast, fungus and bacteria in the small intestine. Medium chain saturated fats are very gentle on the cells that line the gut since they can be passively absorbed without being broken down by digestive enzymes and used for energy without any modification. This source of easy energy is very helpful for healing the lining of the gut. Broth made from the bones of chicken, turkey, duck, beef, lamb pork and/or fish are anti-microbial, anti-inflammatory, and contain nutrients which help rebuild the integrity of the digestive tract. Most importantly, broth is rich in the amino acids proline and glycine, which help regulate digestion, reduce inflammation, and promote healing in every part of the body.
While these dietary changes may seem overwhelming, it is important to remember that making them will keep you healthy, put many diseases into remission, and prevent dozens of other diseases from developing. For the vast majority of people, using diet to prioritize gut health will mean a lifetime of good health.
April 5, 2012 in Categories: Gut Health by ThePaleoMom
If you are concerned that you may have, or could develop, a leaky gut, then changing your diet to one that protects the gut is a natural next step for you. If you are already battling health conditions related to having a leaky gut, then you will have to be more strict with your dietary choices and also address other lifestyle factors like getting good quality sleep, managing stress, finding time for low-strain exercise, and getting outside.
The first and most important thing to do to heal a leaky gut is to stop eating foods that damage and inflame the gut lining! It can take six months or more for the gut to fully heal depending on the extent of the damage, the health of the gut microflora and your individual genetics (for people with Small Intestinal Bacterial Overgrowth, recovery can take up to two years!). Until the gut is completely healthy, it is important to abstain from all grains, all legumes, and all dairy products (some people may tolerate ghee and/or butter from grass-fed sources, but I recommend leaving it out for at least a month before trying it). It is also important to avoid additives in processed foods (many of which irritate the gut) and refined sugars (which promote inflammation). Some people will also need to eliminate vegetables from the nightshade family (tomatoes, eggplants, peppers of all kinds, and especially potatoes), eliminate egg whites (I actually rinse my egg yolks before eating them), and limit nut consumption (other than coconut and macadamias). Changing your diet to avoid gut-irritating foods is critical. But, it is also important to include foods that can reduce inflammation and help heal the damaged gut.
Eat foods that reduce inflammation. It’s very important to be mindful of both your omega-6 and your omega-3 polyunsaturatedfatty acid intake. Omega-6 polyunsaturated fats, which are found in large quantities in modern vegetable oils, meat from grain-fed animals, and many nuts and seeds, increase inflammation. Omega-3 fatty acids, which are found in large quantities in wild-caught fish, pastured/free-range eggs, and meat from pastured animals, decrease inflammation. To help reduce overall inflammation and heal the gut, aim for a 1:1 ratio of omega-3 to omega-6 fatty acid intake in your diet. There are several ways of doing this: you can make sure that all of the meat in your diet is exclusively from grass-fed animals (beef, bison, goat or lamb); you can eat plenty of wild-caught seafood; and/or you can supplement with a good quality fish oil.
Vegetables are rich in anti-oxidants, vitamins and minerals which help control inflammation (and help with just about every other normal function of the body!). Eating a variety of differently colored vegetables, a variety of dark green leafy vegetables, and a variety cruciferous vegetables (broccoli, cauliflower, cabbage, turnip greens, kale, Brussels sprouts, etc.) every day will provide all of the essential vitamins and minerals in a way that is easy for the body to absorb (no more need for a multivitamin!). Fruits, especially berries, are also a good source of antioxidants, vitamins and minerals. However, most people will need to exercise some portion control with fruits due to the high sugar content. I recommend eating vegetables at every meal (it can be a bit strange getting used to eating vegetables at breakfast, but it’s amazing what a difference it makes to how you feel for the whole rest of the day!).
It is also important to make sure you are getting enough Vitamin D. You can achieve this by simply spending some time outside in the sun every day, or from eating liver once or twice per week, or from supplementing with Cod Liver Oil or Vitamin D3 supplements.
Eat foods that restore gut microflora. If you have a leaky and inflamed gut, chances are very good that your resident good bacteria are having trouble too. To help restore their numbers and their diversity, eat as many different good sources of probiotics as possible. You can do this by taking Probiotic supplements and changing brands every time you buy a bottle (the different brands all have different proprietary strains, which helps with increasing your gut microflora diversity). Even better, you can consume probiotic rich foods, like unpasteurized Sauerkraut and other unpasteurized fermented vegetables, Kombucha Tea (my personal favorite), and coconut milk Yogurt or Kefir (which can be a little harder to find in stores but very easy to make at home). All of these can be found at alternative grocery stores (like Whole Foods), and some can be found online, but all can also be made easily and inexpensively at home.
Eat foods that promote healing: As the body tries to heal itself, it’s important to provide it with plenty of good quality protein (needed to make all those new cells and connective tissues) as well as vitamins, minerals and good fats. In this way, the best way to promote healing is to eat a paleo diet that includes wild-caught fish, meat from grass-fed sources, organ meat (preferably from pastured sources), and plenty of vegetables. There are two other healing foods that are very important to include: coconut and bone broth. Antimicrobial short- and medium-chain saturated fats, like those found in coconut oil and other coconut products, help to reduce overgrowth of bad yeast, fungus and bacteria in the small intestine. Medium chain saturated fats are very gentle on the cells that line the gut since they can be passively absorbed without being broken down by digestive enzymes and used for energy without any modification. This source of easy energy is very helpful for healing the lining of the gut. Broth made from the bones of chicken, turkey, duck, beef, lamb pork and/or fish are anti-microbial, anti-inflammatory, and contain nutrients which help rebuild the integrity of the digestive tract. Most importantly, broth is rich in the amino acids proline and glycine, which help regulate digestion, reduce inflammation, and promote healing in every part of the body.
While these dietary changes may seem overwhelming, it is important to remember that making them will keep you healthy, put many diseases into remission, and prevent dozens of other diseases from developing. For the vast majority of people, using diet to prioritize gut health will mean a lifetime of good health.
Fermented food (L. Plantarum) Cured My Eczema | Mr. Heisenbug
L. Plantarum Cured My Eczema | Mr. Heisenbug
I decided to focus on kimchi and sauerkraut, as I consumed them much more frequently than kombucha. And I already knew what the “active ingredient” in these foods would be — fermented vegetables like sauerkraut and kim chi are dominated by the bacterial species Lactobacillus plantarum. In addition to this, I knew that, unlike the commensal bacteria that take up residence in our gut, the primary mechanism of action that exogenous bacteria from fermented foods have in the human body is immune system modulation as they pass through.
And again, eczema is a product of abnormal immune response.
If sauerkraut & kimchi were responsible for the abatement in my eczema, then it was the L. plantarum and its immunomodulating effects.
Well, after multiple flares over the past few months, I finally got around to testing this hypothesis out.
I decided to focus on kimchi and sauerkraut, as I consumed them much more frequently than kombucha. And I already knew what the “active ingredient” in these foods would be — fermented vegetables like sauerkraut and kim chi are dominated by the bacterial species Lactobacillus plantarum. In addition to this, I knew that, unlike the commensal bacteria that take up residence in our gut, the primary mechanism of action that exogenous bacteria from fermented foods have in the human body is immune system modulation as they pass through.
And again, eczema is a product of abnormal immune response.
If sauerkraut & kimchi were responsible for the abatement in my eczema, then it was the L. plantarum and its immunomodulating effects.
Well, after multiple flares over the past few months, I finally got around to testing this hypothesis out.
Saturday, 19 July 2014
Safe Starches - Jaminet and Campbell-McBride are addressing precisely the same issue, but are asserting the opposite. Hmmmm.
Gaps Diet and Safe Starches Controversy, Dr. Natasha Campbell-McBride, Judy Tsafrir M.D., Gaps Practitioner MA | Boston Holistic Psychiatrist & Psychoanalyst
One peculiar and puzzling aspect of this controversy, is that Paul Jaminet asserts that these safe starches are protective against the ravages of dysbiosis. He contends that safe starches facilitate mucous production in the bowel, thereby protecting the wall of the intestine. Without consuming safe starches, the gut wall is vulnerable to damage by pathogenic microflora.
This specifically contradicts the theory of dysbiosis according to Dr. Natasha Campbell-McBride of the GAPS healing protocol. Dr. Campbell-McBride, whose recommendations are in the tradition of the Specific Carbohydrate Diet, teaches that starches which are metabolized to disaccharides, such as all grains, sugar, and starchy vegetables, specifically feed the pathogenic microflora. These pathogens overwhelm the beneficial protective microflora, and thereby compromise the integrity of the bowel wall. This is the root cause of many disease states, as microflora, toxins, and food particles, which should remain within the bowel, diffuse out into the body causing inflammation and infection in the body and the brain. Both Jaminet and Campbell-McBride are addressing precisely the same issue, but are asserting the opposite. Hmmmm.
Upon initiation of the diet, if an individual habitually has consumed a diet high in starchy carbohydrates, there can be a period of metabolic adjustment, when she/he switches to a diet consisting of GAPS permissible foods. In those cases, Dr. Campbell-McBride recommends creating a mixture of equal parts butter or coconut oil and honey, and consuming a spoonful every 30 minutes or so to stabilize blood sugar, until an individual adjusts to the new diet. For those who have been on the diet for an extended period of time, and equate their fatigue with a need for more carbohydrate in their diet, there are GAPS legal foods which are high in carbohydrate, such as winter squash and carrots. I do not personally understand why grains or other non-permitted starchy vegetables such as potatoes or yams are necessary for energy, or for mucous production, for that matter. There are multiple sources of permitted carbohydrates on the the GAPS diet.
For those individuals who are not suffering from insulin resistance or a metabolic disorder, who do not have digestive, psychiatric or auto-immune issues, there seems to be no reason to leave these starches out of the diet. They are delicious, add variety and do not have the damaging effect that gluten has on so many individuals.
The GAPS protocol is not intended as a life long dietary prescription. It is meant to heal psychiatric, digestive and auto-immune conditions. After healing has occurred, an individual may return to eating properly prepared grains and starchy tubers. We all know that one size does not fit all, and that each individual needs to take any health protocol, and adjust it to her/his needs and monitor the effect. It would be wonderful if some omniscient doctor could tell us exactly what we need to do, but we all need to take responsibility for tailoring any dietary recommendations and adapting them to our own unique physiology.
One peculiar and puzzling aspect of this controversy, is that Paul Jaminet asserts that these safe starches are protective against the ravages of dysbiosis. He contends that safe starches facilitate mucous production in the bowel, thereby protecting the wall of the intestine. Without consuming safe starches, the gut wall is vulnerable to damage by pathogenic microflora.
This specifically contradicts the theory of dysbiosis according to Dr. Natasha Campbell-McBride of the GAPS healing protocol. Dr. Campbell-McBride, whose recommendations are in the tradition of the Specific Carbohydrate Diet, teaches that starches which are metabolized to disaccharides, such as all grains, sugar, and starchy vegetables, specifically feed the pathogenic microflora. These pathogens overwhelm the beneficial protective microflora, and thereby compromise the integrity of the bowel wall. This is the root cause of many disease states, as microflora, toxins, and food particles, which should remain within the bowel, diffuse out into the body causing inflammation and infection in the body and the brain. Both Jaminet and Campbell-McBride are addressing precisely the same issue, but are asserting the opposite. Hmmmm.
Upon initiation of the diet, if an individual habitually has consumed a diet high in starchy carbohydrates, there can be a period of metabolic adjustment, when she/he switches to a diet consisting of GAPS permissible foods. In those cases, Dr. Campbell-McBride recommends creating a mixture of equal parts butter or coconut oil and honey, and consuming a spoonful every 30 minutes or so to stabilize blood sugar, until an individual adjusts to the new diet. For those who have been on the diet for an extended period of time, and equate their fatigue with a need for more carbohydrate in their diet, there are GAPS legal foods which are high in carbohydrate, such as winter squash and carrots. I do not personally understand why grains or other non-permitted starchy vegetables such as potatoes or yams are necessary for energy, or for mucous production, for that matter. There are multiple sources of permitted carbohydrates on the the GAPS diet.
For those individuals who are not suffering from insulin resistance or a metabolic disorder, who do not have digestive, psychiatric or auto-immune issues, there seems to be no reason to leave these starches out of the diet. They are delicious, add variety and do not have the damaging effect that gluten has on so many individuals.
The GAPS protocol is not intended as a life long dietary prescription. It is meant to heal psychiatric, digestive and auto-immune conditions. After healing has occurred, an individual may return to eating properly prepared grains and starchy tubers. We all know that one size does not fit all, and that each individual needs to take any health protocol, and adjust it to her/his needs and monitor the effect. It would be wonderful if some omniscient doctor could tell us exactly what we need to do, but we all need to take responsibility for tailoring any dietary recommendations and adapting them to our own unique physiology.
Moderate alcohol consumption is associated with small intestinal bacterial overgrowth, study finds -- ScienceDaily
Moderate alcohol consumption is associated with small intestinal bacterial overgrowth, study finds -- ScienceDaily
Just one drink per day for women -- two for men -- could lead to small intestinal bacterial overgrowth (SIBO) and subsequently cause gastrointestinal symptoms like bloating, gas, abdominal pain, constipation and diarrhea, according to the results of a new study unveiled at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC.
The retrospective review, "Moderate Alcohol Consumption is Associated with Small Intestinal Bacterial Overgrowth," looked at the charts of 198 patients who underwent lactulose hydrogen breath testing (LHBT) to determine the presence of SIBO, and found that any current alcohol consumption was significantly associated with the presence of SIBO -- and neither smoking nor use of heartburn drugs called PPIs was associated with an increased risk of SIBO.
Small intestinal bacterial overgrowth is a condition where abnormally large numbers of bacteria grow in the small intestine. Normally the small intestine contains a relatively low number of bacteria in contrast to the large intestine, which should contain a larger number of bacteria. In patients with SIBO, the abnormally large numbers of bacteria in the small intestine use for their growth many of the nutrients that would otherwise be absorbed.
Just one drink per day for women -- two for men -- could lead to small intestinal bacterial overgrowth (SIBO) and subsequently cause gastrointestinal symptoms like bloating, gas, abdominal pain, constipation and diarrhea, according to the results of a new study unveiled at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC.
The retrospective review, "Moderate Alcohol Consumption is Associated with Small Intestinal Bacterial Overgrowth," looked at the charts of 198 patients who underwent lactulose hydrogen breath testing (LHBT) to determine the presence of SIBO, and found that any current alcohol consumption was significantly associated with the presence of SIBO -- and neither smoking nor use of heartburn drugs called PPIs was associated with an increased risk of SIBO.
Small intestinal bacterial overgrowth is a condition where abnormally large numbers of bacteria grow in the small intestine. Normally the small intestine contains a relatively low number of bacteria in contrast to the large intestine, which should contain a larger number of bacteria. In patients with SIBO, the abnormally large numbers of bacteria in the small intestine use for their growth many of the nutrients that would otherwise be absorbed.
Lentils, gut biome, and the Second Meal Effect
Check out this excellent 3.5-minute video by Dr Michael Greger that doesn't mention resistant starch, but that's what it is he's talking about. Watch how beans not only blunt a BG spike as part of a meal side-by-side with a high-GI carb meal, but persists to blunt BG spikes in subsequent meals or even sugar water, even into the next day.
Incidentally, I have confirmation from some N=1s out there that a ketogenic dieter can remain in ketosis and have zero BG spike consuming up to 30 grams of resistant starch (Bob's Red Mill Potato Starch) per day either along with a Z/VLC meal, or all by itself stirred in water. Accordingly, LCers are just plain ignorant and wrong about Resistant STARCH! (deploy garlic necklaces and crucifixes).
DESCRIPTION: The so-called "lentil effect" or "second meal effect" describes the remarkable effect of beans to help control blood sugar levels hours or even the next day after consumption.
But what about the gas? Check out my blog post Beans and Gas: Clearing the air (http://nutritionfacts.org/2011/12/05/...).
The propionate video I reference is Fawning Over Flora (http://nutritionfacts.org/video/fawni...) with a follow-up Boosting Good Bacteria in the Colon Without Probiotics (http://nutritionfacts.org/video/boost...).
Incidentally, I have confirmation from some N=1s out there that a ketogenic dieter can remain in ketosis and have zero BG spike consuming up to 30 grams of resistant starch (Bob's Red Mill Potato Starch) per day either along with a Z/VLC meal, or all by itself stirred in water. Accordingly, LCers are just plain ignorant and wrong about Resistant STARCH! (deploy garlic necklaces and crucifixes).
DESCRIPTION: The so-called "lentil effect" or "second meal effect" describes the remarkable effect of beans to help control blood sugar levels hours or even the next day after consumption.
But what about the gas? Check out my blog post Beans and Gas: Clearing the air (http://nutritionfacts.org/2011/12/05/...).
The propionate video I reference is Fawning Over Flora (http://nutritionfacts.org/video/fawni...) with a follow-up Boosting Good Bacteria in the Colon Without Probiotics (http://nutritionfacts.org/video/boost...).
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